Using Flory–Huggins phase diagrams as a pre-formulation tool for the production of amorphous solid dispersions: a comparison between hot-melt extrusion and spray drying
Author:
Affiliation:
1. The Drug Delivery and Biomaterials Group, School of Pharmacy, Medical Biology Centre, Queen's University, Belfast, UK
2. School of Pharmacy and Pharmaceutical Sciences, Main Department, Trinity College Dublin, Dublin, Ireland
Abstract
Publisher
Oxford University Press (OUP)
Subject
Pharmaceutical Science,Pharmacology
Link
http://academic.oup.com/jpp/article-pdf/66/2/256/36220670/jphp12141.pdf
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3. Combining SEM, TEM, and micro-Raman techniques to differentiate between the amorphous molecular level dispersions and nanodispersions of a poorly water-soluble drug within a polymer matrix;Karavas;Int J Pharm,2007
4. Physicochemical characterization of hot melt extruded bicalutamide-polyvinylpyrrolidone solid dispersions;Andrews;J Pharm Sci,2010
5. Thermodynamic stability of immiscible polymer blends;Vanhee;Macromolecules,2000
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