BASALIT trial: double-blind placebo-controlled allergen immunotherapy with rBet v 1-FV in birch-related soya allergy

Author:

Treudler R.1,Franke A.2,Schmiedeknecht A.2,Ballmer-Weber B.3,Worm M.4,Werfel T.5,Jappe U.67,Biedermann T.89,Schmitt J.1011,Brehler R.12,Kleinheinz A.13,Kleine-Tebbe J.14,Brüning H.15,Ruëff F.16,Ring J.9,Saloga J.17,Schäkel K.18,Holzhauser T.19,Vieths S.19,Simon J. C.1

Affiliation:

1. Department of Dermatology, Venerology and Allergology; Universität Leipzig; Leipzig Germany

2. Clinical Trial Centre Leipzig (ZKS); Universität Leipzig; Leipzig Germany

3. Allergy Unit; Department of Dermatology; University Hospital Zürich and Centre of Dermatology and Allergology; Luzerner Kantonsspital; Luzern Germany

4. Allergy Center Charité; Department of Dermatology, Venerology and Allergology; Charité - Universitätsmedizin Berlin; Berlin Germany

5. Department of Dermatology and Allergology; MH Hannover; Hannover Germany

6. Division of Clinical & Molecular Allergology Research Center Borstel; Airway Research Center North (ARCN) and Member of the German Center for Lung Research (DZL); Borstel Germany

7. Interdisciplinary Allergy Outpatient Clinic; Department of Internal Medicine; University of Lübeck; Lübeck Germany

8. Department of Dermatology; Universität Tübingen; Tübingen Germany

9. Department of Dermatology and Allergology; Technical University Munich; Munich Germany

10. Department of Dermatology; Medical Faculty Carl Gustav Carus; TU Dresden; Dresden Germany

11. Center for Evidence-based Healthcare; Medical Faculty Carl Gustav Carus; TU Dresden; Dresden Germany

12. Department of Dermatology; Universität Münster; Münster Germany

13. Department of Dermatology; Elbekliniken Buxtehude; Buxtehude Germany

14. Allergy- and Asthma Centre Westend; Berlin Germany

15. Day care clinic for Allergy and Dermatology; Kiel Germany

16. Department of Dermatology and Allergology; Ludwig-Maximilian University; Munich Germany

17. Department of Dermatology; University Medical Center; Johannes Gutenberg-University; Mainz Germany

18. Department of Dermatology; Ruprecht-Karls-Universität Heidelberg; Heidelberg Germany

19. Division of Allergology; Paul-Ehrlich-Institut; Langen Germany

Funder

Bundesministerium für Bildung und Forschung

ALK-Abello

Deutsche Forschungsgemeinschaft

Monsanto Company

Publisher

Wiley

Subject

Immunology,Immunology and Allergy

Reference36 articles.

1. Clinical characterization and IgE profiling of birch (Betula verrucosa)-allergic individuals suffering from allergic reactions to raw fruits and vegetables;Tolkki;J Allergy Clin Immunol Pract,2013

2. High risk of immediate-type reactions to soy drinks in 50 patients with birch pollinosis;Treudler;J Investig Allergol Clin Immunol,2008

3. Soy allergy in perspective;Ballmer-Weber;Curr Opin Allergy Clin Immunol,2008

4. Clinical characteristics of soybean allergy in Europe: a double-blind, placebo-controlled food challenge study;Ballmer-Weber;J Allergy Clin Immunol,2007

5. Bet v 1142-156 is the dominant T-cell epitope of the major birch pollen allergen and important for cross-reactivity with Bet v 1-related food allergens;Jahn-Schmid;J Allergy Clin Immunol,2005

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