Reversal of hepatitis B virus-induced systemic immune tolerance by intrinsic innate immune stimulation
Author:
Affiliation:
1. Institute of Immunopharmacology and Immunotherapy; School of Pharmaceutical Sciences; Shandong University; Jinan Shandong China
2. Institute of Immunology; School of Life Sciences; University of Science and Technology of China; Hefei Anhui China
Funder
Natural Science Foundation of China
Publisher
Wiley
Subject
Gastroenterology,Hepatology
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1111/jgh.12034/fullpdf
Reference42 articles.
1. Hepatitis B virus biology;Seeger;Microbiol. Mol. Biol. Rev.,2000
2. SnapShot: pathways of antiviral innate immunity;Sun;Cell,2010
3. Toll-like receptor-mediated control of HBV replication by nonparenchymal liver cells in mice;Wu;Hepatology,2007
4. Hepatitis B virus polymerase inhibits RIG-I- and Toll-like receptor 3-mediated beta interferon induction in human hepatocytes through interference with interferon regulatory factor 3 activation and dampening of the interaction between TBK1/IKKepsilon and DDX3;Yu;J. Gen. Virol.,2010
5. Hepatitis B virus suppresses toll-like receptor-mediated innate immune responses in murine parenchymal and nonparenchymal liver cells;Wu;Hepatology,2009
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