The global burden, trends and cross‐country inequalities of female breast and gynaecologic cancers: A population based study-Reference-Cited by-同舟云学术

The global burden, trends and cross‐country inequalities of female breast and gynaecologic cancers: A population based study

Published:2024-08-05 Issue: Volume: Page:
ISSN:1470-0328
Container-title:BJOG: An International Journal of Obstetrics & Gynaecology
language:en
Short-container-title:BJOG

Author:

Cheng Liangxing¹²,Wang Zhihong³,Li Rufeng¹,Qiang Min¹,Yang Chen³,Yang Guoer⁴,Xie Yingying⁵,Yuan Ruixia⁴^ORCID,Xu Yungang¹^ORCID

Affiliation:

1. Department of Cell Biology and Genetics, School of Basic Medical Sciences Xi'an Jiaotong University Health Science Center Xi'an China

2. Research Office The First Affiliated Hospital of Zhengzhou University Zhengzhou Henan Province China

3. Department of Gynecology The Second Affiliated Hospital of Zhengzhou University Zhengzhou Henan Province China

4. Clinical Big Data Center The First Affiliated Hospital of Zhengzhou University Zhengzhou Henan Province China

5. Department of Scientific Management The First Affiliated Hospital of Zhengzhou University Zhengzhou Henan Province China

Abstract

AbstractObjectiveTo analyse the global burden, trends and cross‐country inequalities of female breast and gynaecologic cancers (FeBGCs).DesignPopulation‐Based Study.SettingData sourced from the Global Burden of Disease Study 2019.PopulationIndividuals diagnosed with FeBGCs.MethodsAge‐standardised mortality rates (ASMRs), age‐standardised Disability‐Adjusted Life Years (DALYs) rates (ASDRs) and their 95% uncertainty interval (UI) described the burden. Estimated annual percentage changes (EAPCs) and their confidence interval (CI) of age‐standardised rates (ASRs) illustrated trends. Social inequalities were quantified using the Slope Index of Inequality (SII) and Concentration Index.Main Outcome MeasuresThe main outcome measures were the burden of FeBGCs and the trends in its inequalities over time.ResultsIn 2019, the ASDRs per 100 000 females were as follows: breast cancer: 473.83 (95% UI: 437.30–510.51), cervical cancer: 210.64 (95% UI: 177.67–234.85), ovarian cancer: 124.68 (95% UI: 109.13–138.67) and uterine cancer: 210.64 (95% UI: 177.67–234.85). The trends per year from 1990 to 2019 were expressed as EAPCs of ASDRs and these: for Breast cancer: −0.51 (95% CI: −0.57 to −0.45); Cervical cancer: −0.95 (95% CI: −0.99 to −0.89); Ovarian cancer: −0.08 (95% CI: −0.12 to −0.04); and Uterine cancer: −0.84 (95% CI: −0.93 to −0.75). In the Social Inequalities Analysis (1990–2019) the SII changed from 689.26 to 607.08 for Breast, from −226.66 to −239.92 for cervical, from 222.45 to 228.83 for ovarian and from 74.61 to 103.58 for uterine cancer. The concentration index values ranged from 0.2 to 0.4.ConclusionsThe burden of FeBGCs worldwide showed a downward trend from 1990 to 2019. Countries or regions with higher Socio‐demographic Index (SDI) bear a higher DALYs burden of breast, ovarian and uterine cancers, while those with lower SDI bear a heavier burden of cervical cancer. These inequalities increased over time.

Publisher

Wiley

Link

https://obgyn.onlinelibrary.wiley.com/doi/pdf/10.1111/1471-0528.17925

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