Pelvic vein incompetence and chronic pelvic pain: a case–control study

Abstract

AbstractObjectiveTo investigate the association between chronic pelvic pain (CPP) and pelvic vein incompetence (PVI) or pelvic varices.DesignCase–control study.SettingGynaecology and vascular surgery services in two teaching hospitals in north‐west England.SampleA total of 328 premenopausal women (aged 18–54 years), comprising 164 women with CPP and 164 matched controls with no history of CPP.MethodsSymptom and quality‐of‐life questionnaires and transvaginal duplex ultrasound for PVI and pelvic varices.Main outcome measuresVenous reflux of >0.7 s in the ovarian or internal iliac veins (primary outcome) and presence of pelvic varices (secondary outcome). Statistical analysis compared the prevalence of PVI between women with and without CPP using the two‐sided chi‐square test. Logistic regression was used to compare the odds of having PVI and pelvic varices between women with and without CPP.ResultsPelvic vein incompetence was found on transvaginal duplex ultrasound in 101/162 (62%) women with CPP, compared with 30/164 (19%) asymptomatic controls (OR 6.79, 95% CI 4.11–11.47, p < 0.001). Forty‐three of 164 (27%) women with CPP had pelvic varices compared with three of 164 (2%) asymptomatic women (OR 18.9, 95% CI 5.73–62.7, p < 0.001).ConclusionsThere was a significant association between PVI, as detected by transvaginal duplex imaging, and CPP. Pelvic varices were strongly associated with CPP and were infrequently seen in control patients. These results justify further evaluation of PVI and its treatment in well‐designed research.