The Emergency Medicine Debate on tPA for Stroke: What Is Best for Our Patients? Efficacy in the First Three Hours

Author:

Miller Joseph B.1,Heitsch Laura2,Siket Matthew S.3,Schrock Jon W.4,Wira Charles R.5,Lewandowski Christopher1,Madsen Tracy E.3,Merck Lisa H.3,Wright David W.6,

Affiliation:

1. Department of Emergency Medicine; Henry Ford Hospital; Detroit MI

2. Department of Emergency Medicine; Washington University School of Medicine; St. Louis MO

3. Department of Emergency Medicine; Alpert Medical School of Brown University; Providence RI

4. Department of Emergency Medicine; Case Western Reserve University School of Medicine; Cleveland OH

5. Department of Emergency Medicine; Yale School of Medicine; New Haven CT

6. Department of Emergency Medicine; Emory University; Atlanta GA

Publisher

Wiley

Subject

Emergency Medicine,General Medicine

Reference31 articles.

1. Policy Clinical: Use of intravenous tPA for the management of acute ischemic stroke in the emergency department;Ann Emerg Med,2013

2. Draft: Use of Intravenous tPA for the Management of Acute Ischemic Stroke in the Emergency Department https://www.google.com/url?sa=t&rct=j&q=&esrc=s&source=web&cd=1&cad=rja&uact=8&ved=0CB4QFjAA&url=http%3A%2F%2Fwww.acep.org%2FuploadedFiles%2FACEP%2FpracticeResources%2FtPA%2520for%2520stroke%2520draft%25201-5-15.doc&ei=AyFdVbKOPJOxyQSR24LgDw&usg=AFQjCNHVstPLOY1BKl2TRqqhRqyIwIqb3A&sig2=fL_QkI9cBPJWLfYUbjwKTw

3. Tissue plasminogen activator for acute ischemic stroke;The National Institute of Neurological Disorders and Stroke rt-PA Stroke Study Group;N Engl J Med,1995

4. A graphic reanalysis of the NINDS Trial;Hoffman;Ann Emerg Med,2009

5. Time to treatment with intravenous alteplase and outcome in stroke: an updated pooled analysis of ECASS, ATLANTIS, NINDS, and EPITHET trials;Lees;Lancet,2010

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