Rapid brief feedback intracerebral stimulation based on real-time desynchronization detection preceding seizures stops the generation of convulsive paroxysms

Author:

Salam Muhammad T.1,Kassiri Hossein1,Genov Roman1,Perez Velazquez Jose L.2

Affiliation:

1. Department of Electrical and Computer Engineering; University of Toronto; Toronto Ontario Canada

2. Neuroscience & Mental Health Programme and Division of Neurology; Hospital for Sick Children; Institute of Medical Science and Department of Paediatrics; University of Toronto; Toronto Ontario Canada

Funder

Natural Sciences and Engineering Research Council of Canada (NSERC)

Ontario Brain Institute (OBI)

Publisher

Wiley

Subject

Clinical Neurology,Neurology

Reference51 articles.

1. Metastability of brain states and the many routes to seizures: numerous causes, same result;Perez Velazquez;Recent Res Dev Biophys,2004

2. Focus on desynchronization rather than excitability: a new strategy for intraencephalic electrical stimulation;Medeiros;Epilepsy Behav,2014

3. Pathways of translation: deep brain stimulation;Gionfriddo;Clin Transl Sci,2013

4. Effects of direct brain stimulation depend on seizure dynamics;Jiruska;Epilepsia,2010

5. Therapeutic brain stimulation for epilepsy;Lockman;Neurol Clin,2009

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