Results from a large multinational clinical trial (guardian™1) using prophylactic treatment with turoctocog alfa in adolescent and adult patients with severe haemophilia A: safety and efficacy

Author:

Lentz S. R.1,Misgav M.2,Ozelo M.3,Šalek S. Z.4,Veljkovic D.5,Recht M.6,Cerqueira M.7,Tiede A.8,Brand B.9,Mancuso M. E.10,Seremetis S.11,Lindblom A.12,Martinowitz U.2

Affiliation:

1. Department of Internal Medicine; The University of Iowa Carver College of Medicine; Iowa City; IA; USA

2. National Hemophilia Center; Chaim Sheba Medical Center Affiliated to the Sackler School of Medicine; Tel Aviv University; Tel Aviv; Israel

3. IHTC ‘Claudio L. P. Correa’; INCT do Sangue Hemocentro UNICAMP; University of Campinas; Sao Paulo; Brazil

4. National Referral Haemophilia and Thrombophilia Centre; University Hospital Centre; Zagreb; Croatia

5. Transfusion Medicine Department; Institute for Mother and Child Health Care of Serbia; Belgrade; Serbia

6. The Hemophilia Center; Oregon Health & Science University; Portland; OR; USA

7. HEMORIO; Rio de Janeiro; Brazil

8. Medizinische Hochschule Hannover; Hannover; Germany

9. Division of Hematology; University Hospital; Zürich; Switzerland

10. Angelo Bianchi Bonomi Hemophilia and Thrombosis Center; Fondazione IRCCS Ca' Granda; Ospedale Maggiore Policlinico; Milan; Italy

11. Haemophilia R&D Portfolio; Novo Nordisk Inc.; Princeton; NJ; USA

12. Medical & Science Haemophilia; Novo Nordisk A/S; Soeborg; Denmark

Publisher

Wiley

Subject

Genetics(clinical),Hematology,General Medicine

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