Cystathionine‐gamma‐lyase overexpression in T cells enhances antitumor effect independently of cysteine autonomy-Reference-Cited by-同舟云学术

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Cystathionine‐gamma‐lyase overexpression in T cells enhances antitumor effect independently of cysteine autonomy

Published:2021-03-12 Issue:5 Volume:112 Page:1723-1734
ISSN:1347-9032
Container-title:Cancer Science
language:en
Short-container-title:Cancer Sci

Author:

Lancien Melanie¹²,Gueno Lucile¹²,Salle Sonia¹²,Merieau Emmanuel¹²,Beriou Gaelle¹²,Nguyen Tuan H.¹²,Abidi Ahmed¹³,Dilek Nahzli⁴,Solomon Pierre¹,Poschmann Jeremie¹,Michielin Olivier⁴⁵⁶,Vuillefroy de Silly Romain⁵,Vanhove Bernard¹⁷,Louvet Cedric¹^ORCID

Affiliation:

1. Inserm, Centre de Recherche en Transplantation et Immunologie, UMR 1064 ITUN Université de Nantes Nantes France

2. LabEx IGO “Immunotherapy, Graft, Oncology” Nantes France

3. Faculty of Sciences, Tunis University of Tunis El Manar Tunis Tunisia

4. Molecular Modeling Group SIB Swiss Institute for Bioinformatics Lausanne Switzerland

5. The Ludwig Institute for Cancer Research University of Lausanne Epalinges Switzerland

6. Department of Oncology University of Lausanne and Centre Hospitalier Universitaire Vaudois (CHUV) Lausanne Switzerland

7. Xenothera Nantes France

Funder

Agence Nationale de la Recherche

Fondation pour la Recherche Médicale

Publisher

Wiley

Subject

Cancer Research,Oncology,General Medicine

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1111/cas.14862

Reference32 articles.

1. Programming CAR-T cells to kill cancer

2. Engineering Chimeric Antigen Receptor T-Cells for Racing in Solid Tumors: Don’t Forget the Fuel

3. Suppression of Glut1 and Glucose Metabolism by Decreased Akt/mTORC1 Signaling Drives T Cell Impairment in B Cell Leukemia

4. Coexpressed Catalase Protects Chimeric Antigen Receptor–Redirected T Cells as well as Bystander Cells from Oxidative Stress–Induced Loss of Antitumor Activity

5. The Tumor Microenvironment Represses T Cell Mitochondrial Biogenesis to Drive Intratumoral T Cell Metabolic Insufficiency and Dysfunction

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1. Cystine deprivation triggers CD36-mediated ferroptosis and dysfunction of tumor infiltrating CD8+ T cells;Cell Death & Disease;2024-02-15

2. Differential and cooperative effects of IL-25 and IL-33 on T helper cells contribute to cryptococcal virulence and brain infection;Scientific Reports;2023-06-19

3. Recent advances in the role of endogenous hydrogen sulphide in cancer cells;Cell Proliferation;2023-03-16

4. Physiological roles of hydrogen sulfide in mammalian cells, tissues, and organs;Physiological Reviews;2023-01-01

5. High-throughput in situ perturbation of metabolite levels in the tumor micro-environment reveals favorable metabolic condition for increased fitness of infiltrated T-cells;Frontiers in Cell and Developmental Biology;2022-12-22

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