Unexpectedly long half-life of metformin elimination in cases of metformin accumulation
Author:
Affiliation:
1. Service d'Endocrinologie-Nutrition; Hôpital Sud; Amiens France
2. Unité INSERM 1088; Université de Picardie Jules Verne; Amiens France
3. Laboratoire de Pharmacologie clinique; Hôpital Sud; Amiens France
Publisher
Wiley
Subject
Endocrinology,Endocrinology, Diabetes and Metabolism,Internal Medicine
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1111/dme.12959/fullpdf
Reference14 articles.
1. Clinical pharmacokinetics of metformin;Graham;Clin Pharmacokinet,2011
2. Kinetics of plasma and erythrocyte metformin after acute administration in healthy subjects;Robert;Diabetes Metab,2003
3. Measurement of metformin concentration in erythrocytes: clinical implications;Lalau;Diabetes Obes Metab,2003
4. Interpreting the consequences of metformin accumulation in an emergency context: impact of the time frame on the blood metformin levels;Lalau;Int J Endocrinol,2014
5. FDA label approved on 07/19/2013 (PDF) for Metformin Hydrochloride www.accessdata.fda.gov/drugsatfda_docs/label/2013/091664Orig1s000lbl.pdf
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