Metipranolol promotes structure and function of retinal photoreceptors in the rd10 mouse model of human retinitis pigmentosa

Author:

Kanan Yogita1,Khan Mahmood1,Lorenc Valeria E.1,Long Da1,Chadha Rishi1,Sciamanna Jason1,Green Ken2,Campochiaro Peter A.1ORCID

Affiliation:

1. Departments of Ophthalmology and Neuroscience; The Wilmer Eye Institute; Johns Hopkins University School of Medicine; Baltimore Maryland USA

2. Alimera Sciences; 6120 Windward Parkway Alpharetta Georgia USA

Funder

National Eye Institute

Publisher

Wiley

Subject

Cellular and Molecular Neuroscience,Biochemistry

Reference31 articles.

1. Cataract associated with an hereditary retinal lesion in rats;Bourne;Br. J. Ophthalmol.,1938

2. Retinal degeneration in the rd mouse caused by a defect in the beta subunit of rod cGMP-phosphodiesterase;Bowes;Nature,1990

3. Oxygen consumption in the inner and outer retina of the cat;Braun;Invest. Ophthalmol. Vis. Sci.,1995

4. Is there excess oxidative stress and damage in eyes of patients with retinitis pigmentosa;Campochiaro;Antioxid. Redox Signal.,2015

5. Differential effects of the rd mutation on rods and cones in the mouse retina;Carter-Dawson;Invest. Ophthalmol. Vis. Sci.,1978

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