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Identification of driver and subclonal mutations in ASXL1 and IDH1/IDH2 genes in an Argentine series of patients with myelofibrosis

  • Published:2018-05-14 Issue:4 Volume:40 Page:e82-e86
  • ISSN:1751-5521
  • Container-title:International Journal of Laboratory Hematology
  • language:en
  • Short-container-title:Int J Lab Hem

Author:

Scheps K.1,Meyer C.1,Bestach Y.1,Enrico A.2,Bengió R.3,Rodríguez-Zubieta M.4,Rivas M.5,De Brasi C.13,Larripa I.1ORCID

Affiliation:

1. Laboratorio de Genética; IMEX; CONICET-Academia Nacional de Medicina; Buenos Aires Argentina

2. Hospital Italiano La Plata; La Plata Pcia, de Buenos Aires Argentina

3. IIHEMA; Academia Nacional de Medicina; Ciudad de Buenos Aires Argentina

4. Servicio de Anatomía Patológica; Hospital Universitario Austral; Buenos Aires Pcia. de Buenos Aires Argentina

5. Servicio de Hematología y Trasplante de Médula Ósea; Hospital Universitario Austral; Buenos Aires Argentina

Funder

Consejo Nacional de Investigaciones Científicas y Técnicas

Agencia Nacional de Promoción Científica y Tecnológica

Instituto Nacional del Cáncer

Publisher

Wiley

Subject

Biochemistry (medical),Clinical Biochemistry,Hematology,General Medicine

Reference12 articles.

1. Primary myelofibrosis: 2017 update on diagnosis, risk-stratification, and management;Tefferi;Am J Hematol,2016

2. Somatic mutations of calreticulin in myeloproliferative neoplasms;Klampfl;N Engl J Med,2013

3. CALR vs JAK2 vs MPL-mutated or triple-negative myelofibrosis: clinical, cytogenetic and molecular comparisons;Tefferi;Leukemia,2014

4. ASXL1 mutations in myeloid neoplasms: pathogenetic considerations, impact on clinical outcomes and survival;Alvarez Argote;Curr Med Res Opin,2017

5. CALR, JAK2, and MPL mutation profile in patients with four different subtypes of myeloproliferative neoplasms;Kim;Am J Clin Pathol,2015
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