Macrocytosis, Macrocytic Anemia, and Genetic Polymorphisms of Alcohol Dehydrogenase-1B and Aldehyde Dehydrogenase-2 in Japanese Alcoholic Men

Author:

Yokoyama Akira1,Yokoyama Tetsuji2,Brooks Philip J.3,Mizukami Takeshi1,Matsui Toshifumi14,Kimura Mitsuru1,Matsushita Sachio1,Higuchi Susumu1,Maruyama Katsuya1

Affiliation:

1. National Hospital Organization Kurihama Medical and Addiction Center; Kanagawa Japan

2. Department of Health Promotion; National Institute of Public Health; Saitama Japan

3. Division of Metabolism and Health Effects and Laboratory of Neurogenetics; National Institute on Alcohol Abuse and Alcoholism; National Institutes of Health; Bethesda Maryland

4. Department of Geriatric Medicine; Kyorin University Hospital; Tokyo Japan

Publisher

Wiley

Subject

Psychiatry and Mental health,Toxicology,Medicine (miscellaneous)

Reference44 articles.

1. American Psychiatric Association 1994 Diagnostic and Statistical Manual of Mental Disorders 4th ed American Psychiatric Association Washington, DC

2. The alcohol flushing response: an unrecognized risk factor of esophageal cancer from alcohol consumption;Brooks;PLoS Med,2009

3. Sex-related differences in the haematological effects of excessive alcohol consumption;Chalmers;J Clin Pathol,1980

4. Interaction between the functional polymorphisms of the alcohol-metabolism genes in protection against alcoholism;Chen;Am J Hum Genet,1999

5. Effect of abstinence on the blood acetaldehyde response to a test dose of alcohol in alcoholics;Padova;Alcohol Clin Exp Res,1987

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