Platelet-derived growth factor receptor β (PDGFRβ) immunohistochemistry highlights activated bone marrow stroma and is potentially predictive for fibrosis progression in prefibrotic myeloproliferative neoplasia

Author:

Méhes Gábor1,Tzankov Alexandar2,Hebeda Konnie3,Anagnostopoulos Ioannis4,Krenács László5,Bedekovics Judit1

Affiliation:

1. Department of Pathology; University of Debrecen; Debrecen Hungary

2. Institute of Pathology; University Hospital; Basel Switzerland

3. Department of Pathology; Radboud University Medical Centre; Nijmegen the Netherlands

4. Institute of Pathology; Charité-University Medicine Berlin; Campus Charité Mitte; Berlin Germany

5. Laboratory of Tumor Pathology and Molecular Diagnostics; Szeged Hungary

Funder

European Union

European Social Fund

Publisher

Wiley

Subject

General Medicine,Histology,Pathology and Forensic Medicine

Reference19 articles.

1. Bone marrow fibrosis: pathophysiology and clinical significance of increased bone marrow stromal fibres;Kuter;Br. J. Haematol.,2007

2. Myeloproliferative neoplasia: a review of clinical criteria and treatment;Koopmans;Neth. J. Med.,2012

3. Myelofibrosis in chronic myeloproliferative disorders - dynamics and clinical impact;Thiele;Histol. Histopathol.,2006

4. European consensus on grading bone marrow fibrosis and assessment of cellularity;Thiele;Haematologica,2005

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