Glucotoxicity inhibits cAMP-protein kinase A-potentiated glucose-stimulated insulin secretion in pancreaticβ-cells葡萄糖毒性抑制cAMP-PKA通路促进的胰岛β细胞中血糖刺激的胰岛素分泌
Author:
Affiliation:
1. Diabetes Center of Shenzhen University and School of Medicine; Shenzhen University; Shenzhen China
Publisher
Wiley
Subject
Endocrinology, Diabetes and Metabolism
Reference35 articles.
1. Impaired beta-cell functions induced by chronic exposure of cultured human pancreatic islets to high glucose;Marshak;Diabetes,1999
2. Glucose induces beta-cell apoptosis via upregulation of the Fas receptor in human islets;Maedler;Diabetes,2001
3. Increase in insulin response after treatment of overt maturity-onset diabetes is independent of the mode of treatment;Kosaka;Diabetologia,1980
4. Beta-cell glucose toxicity, lipotoxicity, and chronic oxidative stress in type 2 diabetes;Robertson;Diabetes,2004
5. Islet beta cell failure in type 2 diabetes;Prentki;J Clin Invest,2006
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