Development potential of selenium in the prevention and treatment of bovine endometritis

Author:

Li Hanqing123,Dong Junsheng123,Wang Zi123,Cui Luying123,Liu Kangjun123,Guo Long123,Li Jianji123ORCID,Wang Heng123

Affiliation:

1. College of Veterinary Medicine Jiangsu Co‐Innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, Yangzhou University Yangzhou China

2. Joint International Research Laboratory of Agriculture and Agri‐Product Safety of the Ministry of Education Yangzhou China

3. International Research Laboratory of Prevention and Control of Important Animal Infectious Diseases and Zoonotic Diseases of Jiangsu Higher Education Institutions Yangzhou University Yangzhou China

Abstract

AbstractEndometritis is a common postpartum disease in cows. It delays uterine involution and impairs normal physiological function. This can result in long‐term or even lifelong infertility and cause significant losses to the dairy farming industry. Traditional treatments like antibiotics possess certain shortcomings, such as antibiotic residues, the abuse of antibiotics, and increased antimicrobial resistance of pathogens. Alternative treatment strategies are needed to minimize the utilization of antibiotics in dairy production. As an essential trace element in animals, selenium (Se) plays a vital role in regulating immune function, the inflammatory response, and oxidative stress, affecting the speed and completeness of tissue repair. This paper reviewed previous studies to analyse the potential of Se in the prevention and treatment of bovine endometritis, aiming to provide a new direction to increase production capacity in the future.

Funder

National Key Research and Development Program of China

National Natural Science Foundation of China

Higher Education Discipline Innovation Project

Yangzhou University

Priority Academic Program Development of Jiangsu Higher Education Institutions

Publisher

Wiley

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