Quantitative pharmacokinetic-pharmacodynamic modelling of baclofen-mediated cardiovascular effects using BP and heart rate in rats
Author:
Affiliation:
1. Drug Safety and Metabolism; AstraZeneca-US; Waltham MA USA
2. Analytical Group, Cancer Chemistry; AstraZeneca-US; Waltham MA USA
Publisher
Wiley
Subject
Pharmacology
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1111/bph.13561/fullpdf
Reference50 articles.
1. Activation of thermogenesis of brown fat in rats by baclofen;Addae;Neuropharmacology,1986
2. The Concise Guide to PHARMACOLOGY 2015/16: G protein-coupled receptors;Alexander;Br J Pharmacol,2015
3. Cerebral oxygenation and hyperthermia;Bain;Front Physiol,2014
4. Baclofen prevents MDMA-induced rise in core body temperature in rats;Bexis;Drug Alcohol Depend,2004
5. GABA(B) receptor-mediated effects on vagal pathways to the lower oesophageal sphincter and heart;Blackshaw;Br J Pharmacol,2000
Cited by 13 articles. 订阅此论文施引文献 订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献
1. Overview of the ICH E14/S7B: Questions and Answers;Drug Discovery and Evaluation: Safety and Pharmacokinetic Assays;2024
2. 2000–2023 over two decades of ICH S7A: has the time come for a revamp?;Regulatory Toxicology and Pharmacology;2023-03
3. Modeling approaches for reducing safety-related attrition in drug discovery and development: a review on myelotoxicity, immunotoxicity, cardiovascular toxicity, and liver toxicity;Expert Opinion on Drug Discovery;2021-06-28
4. An Integrative Approach for Improved Assessment of Cardiovascular Safety Data;Journal of Pharmacology and Experimental Therapeutics;2021-03-01
5. A case report on the effects of atropine against baclofen in inguinal hernia surgery patient;International Journal of Surgery Open;2021-01
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线，采集、加工和组织学术论文而形成的新型学术文献查询和分析系统，可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容，当前同舟云学术共收录了国内外主流学术期刊6万余种，收集的期刊论文及会议论文总量共计约1.5亿篇，并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询！咨询电话：010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3