The pharmacokinetics of pimobendan enantiomers after oral and intravenous administration of racemate pimobendan formulations in healthy dogs
Author:
Affiliation:
1. Translational Research and Animal Clinical Trial Study (TRACTS) Group; Faculty of Veterinary and Agricultural Sciences; University of Melbourne; Werribee Vic. Australia
2. Racing Analytical Services Ltd; Flemington Vic. Australia
Funder
Apex Laboratories Pty. Ltd.
Publisher
Wiley
Subject
General Veterinary,Pharmacology
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1111/jvp.12235/fullpdf
Reference21 articles.
1. Plasma and red blood cells pharmacokinetics of pimobendan enantiomers in healthy Chinese;Chu;European Journal of Clinical Pharmacology,1995a
2. Pharmacokinetics and pharmacodynamics of pimobendan in patients with dilated cardiomyopathy and congestive heart failure after single and repeated oral dosing;Chu;Clinical Pharmacology and Therapeutics,1995b
3. Cardiovascular effect and simultaneous pharmacokinetic and pharmacodynamic modeling of pimobendan in healthy normal subjects;Chu;Drug Metabolism and Disposition,1999
4. Pharmacodynamic and pharmacokinetic difference between drug enantiomers in humans: an overview;Drayer;Clinical Pharmacology and Therapeutics,1986
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