Efficacy, safety, and pharmacokinetics of simeprevir, daclatasvir, and ribavirin in patients with recurrent hepatitis C virus genotype 1b infection after orthotopic liver transplantation: The Phase II SATURN study

Author:

Forns Xavier1,Berenguer Marina2,Herzer Kerstin3,Sterneck Martina4,Donato Maria Francesca5,Andreone Pietro6,Fagiuoli Stefano7,Cieciura Tomasz8,Durlik Magdalena9,Calleja Jose Luis10,Mariño Zoe1,Shukla Umesh11,Verbinnen Thierry12,Lenz Oliver12,Ouwerkerk-Mahadevan Sivi13,Peeters Monika12,Janssen Katrien12,Kalmeijer Ronald11,Jessner Wolfgang11

Affiliation:

1. Liver Unit, Hospital Clinic, IDIBAPS and CIBEREHD; University of Barcelona; Barcelona Spain

2. Department of Digestive Diseases, Hepatology and Liver Transplantation Unit; La Fe University Hospital and CIBEREHD; Valencia Spain

3. Department of General, Visceral and Transplantation Surgery and Department of Gastroenterology and Hepatology; University Hospital Essen; University Duisburg-Essen; Essen Germany

4. Department of Hepatobiliary and Transplant Surgery; University Medical Center Hamburg-Eppendorf; Hamburg Germany

5. Division of Digestive Diseases; IRCCS Maggiore Hospital; Milan Italy

6. Department of Medical and Surgical Sciences; University of Bologna; Bologna Italy

7. Gastroenterology and Transplant Hepatology; Papa Giovanni XXIII Hospital; Bergamo Italy

8. Department of Immunology, Transplant Medicine and Internal Diseases; Transplantation Institute; Medical University of Warsaw; Warsaw Poland

9. Department of Transplantation Medicine and Nephrology; Transplantation Institute; Medical University of Warsaw; Warsaw Poland

10. Liver Unit; Hospital Universitario Puerta de Hierro, CIBEREHD and IDIPHIM; Madrid Spain

11. Janssen Research & Development; LLC; Titusville NJ USA

12. Janssen Pharmaceutica NV; Beerse Belgium

13. Janssen Research & Development; Beerse Belgium

Funder

Janssen

Publisher

Wiley

Subject

Infectious Diseases,Transplantation

Reference31 articles.

1. Liver transplantation and hepatitis C;Rubin;Clin Res Hepatol Gastroenterol,2011

2. Hepatitis C virus kinetics during and immediately after liver transplantation;Garcia-Retortillo;Hepatology,2002

3. Hepatitis C recurrence: The Achilles heel of liver transplantation;Howell;Transpl Infect Dis,2014

4. Liver transplantation in the setting of chronic HCV;Terrault;Best Pract Res Clin Gastroenterol,2012

5. Recurrence of hepatitis C after liver transplantation;Vinaixa;Ann Gastroenterol,2013

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