Post-Genome-Wide Association Study Challenges for Lipid Traits: Describing Age as a Modifier of Gene-Lipid Associations in the Population Architecture Using Genomics and Epidemiology (PAGE) Study

Author:

Dumitrescu Logan1,Carty Cara L.2,Franceschini Nora3,Hindorff Lucia A.4,Cole Shelley A.5,Bůžková Petra6,Schumacher Fredrick R.7,Eaton Charles B.8,Goodloe Robert J.1,Duggan David J.9,Haessler Jeff2,Cochran Barbara10,Henderson Brian E.7,Cheng Iona11,Johnson Karen C.12,Carlson Chris S.2,Love Shelly-Ann3,Brown-Gentry Kristin1,Nato Alejandro Q.13,Quibrera Miguel14,Anderson Garnet2,Shohet Ralph V.15,Ambite José Luis16,Wilkens Lynne R.17,Marchand Loïc Le17,Haiman Christopher A.7,Buyske Steven18,Kooperberg Charles2,North Kari E.319,Fornage Myriam2021,Crawford Dana C.122

Affiliation:

1. Center for Human Genetics Research; Vanderbilt University; Nashville TN

2. Public Health Sciences; Fred Hutchinson Cancer Research Center; Seattle WA

3. Department of Epidemiology; University of North Carolina; Chapel Hill NC

4. Office of Population Genomics; National Human Genome Research Institute; Bethesda MD

5. Department of Genetics; Texas Biomedical Research Institute; San Antonio TX

6. Department of Biostatistics; University of Washington; Seattle WA

7. Department of Preventive Medicine; Keck School of Medicine, University of Southern California; Los Angeles CA

8. Department of Family Medicine; Warren Alpert Medical School, Brown University; Providence RI

9. Translational Genomics Research Institute; Phoenix AZ

10. Baylor College of Medicine; Houston TX

11. Cancer Prevention Institute of California; Fremont CA

12. Department of Preventive Medicine; University of Tennessee Health Science Center; Memphis TN

13. Department of Genetics; Rutgers University; Piscataway NJ

14. Gillings School of Public Health; University of North Carolina; Chapel Hill NC

15. John A. Burns School of Medicine; University of Hawaii; Honolulu HI

16. Information Sciences Institute; University of Southern California; Marina del Rey CA

17. Epidemiology Program; University of Hawaii Cancer Center; Honolulu HI

18. Department of Genetics and Department of Statistics; Rutgers University; Piscataway NJ

19. Carolina Center for Genome Sciences; University of North Carolina at Chapel Hill; Chapel Hill NC

20. Division of Epidemiology, Human Genetics, and Environmental Sciences, School of Public Health; University of Texas Health Sciences Center at Houston; TX

21. Institute of Molecular Medicine; University of Texas Health Sciences Center at Houston; TX

22. Department of Molecular Physiology and Biophysics; Vanderbilt University; Nashville TN

Funder

National Human Genome Research Institute (NHGRI)

NHGRI PAGE and its NHGRI ARRA supplement

National Cancer Institute

NHLBI; NIH; and U.S. Department of Health and Human Services

NHLBI

National Institutes of Health, NHLBI

National Institute on Aging

Publisher

Wiley

Subject

Genetics (clinical),Genetics

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