Optimizing pain management in breast cancer care: Utilizing ‘All of Us’ data and deep learning to identify patients at elevated risk for chronic pain

Abstract

AbstractPurposeThe aim of the study was to develop a prediction model using deep learning approach to identify breast cancer patients at high risk for chronic pain.DesignThis study was a retrospective, observational study.MethodsWe used demographic, diagnosis, and social survey data from the NIH ‘All of Us’ program and used a deep learning approach, specifically a Transformer‐based time‐series classifier, to develop and evaluate our prediction model.ResultsThe final dataset included 1131 patients. We evaluated the deep learning prediction model, which achieved an accuracy of 72.8% and an area under the receiver operating characteristic curve of 82.0%, demonstrating high performance.ConclusionOur research represents a significant advancement in predicting chronic pain among breast cancer patients, leveraging deep learning model. Our unique approach integrates both time‐series and static data for a more comprehensive understanding of patient outcomes.Clinical RelevanceOur study could enhance early identification and personalized management of chronic pain in breast cancer patients using a deep learning‐based prediction model, reducing pain burden and improving outcomes.