The prevalence of vitamin D deficiency and associated factors in first‐episode psychosis

Author:

Tsiglopoulos Jonathan12ORCID,Pearson Nicholas12,Mifsud Nathan12,Castagnini Emily12,Allott Kelly12ORCID,Thompson Andrew12,Killackey Eoin12ORCID,McGorry Patrick12,O'Donoghue Brian123ORCID

Affiliation:

1. Orygen Parkville Victoria Australia

2. Centre for Youth Mental Health, University of Melbourne Victoria Australia

3. Department of Psychiatry University College Dublin Dublin Ireland

Abstract

AbstractAimVitamin D deficiency is prevalent in people with established psychotic disorders, but less is known about vitamin D levels in people with first‐episode psychosis (FEP). This study aimed to determine the prevalence of vitamin D deficiency in people with FEP and identify the factors associated with vitamin D status.MethodsThis was a prospective cohort study nested within a randomized controlled trial, which included 37 young people with an FEP with minimal antipsychotic medication exposure.ResultsTwenty‐four percent of participants were vitamin D deficient, and a further 30% were vitamin D insufficient. There was no association between vitamin D and demographic factors or clinical symptoms (positive, negative, general psychopathology and depressive symptoms) or cognition and functioning. However, vitamin D levels were associated with season of sampling.ConclusionsConsidering the longer‐term adverse effects associated with vitamin D deficiency, it is warranted to ensure this clinical population receives supplementation if indicated.

Funder

University of Melbourne

Publisher

Wiley

Subject

Biological Psychiatry,Psychiatry and Mental health,Pshychiatric Mental Health

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