Thorough QT study of the effect of oral moxifloxacin on QTcinterval in the fed and fasted state in healthy Japanese and Caucasian subjects-Reference-Cited by-同舟云学术

Thorough QT study of the effect of oral moxifloxacin on QTcinterval in the fed and fasted state in healthy Japanese and Caucasian subjects

Published:2013-12-20 Issue:1 Volume:77 Page:170-179
ISSN:0306-5251
Container-title:British Journal of Clinical Pharmacology
language:en
Short-container-title:Br J Clin Pharmacol

Author:

Taubel Jorg¹,Ferber Georg²,Lorch Ulrike¹,Batchvarov Velislav³,Savelieva Irina³,Camm A. John³

Affiliation:

1. Richmond Pharmacology Ltd; London UK

2. Statistik Georg Ferber GmbH; Riehen Switzerland

3. Department of Cardiological Sciences; St George's University of London; London UK

Publisher

Wiley

Subject

Pharmacology (medical),Pharmacology

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1111/bcp.12168/fullpdf

Reference24 articles.

1. Update on the evaluation of a new drug for effects on cardiac repolarization in humans: issues in early drug development;Salvi;Br J Pharmacol,2010

2. ICH E14 The Clinical Evaluation of QT/QT c Interval Prolongation and Pro-arrhythmic Potential for Non-antiarrhythmic Drugs 2005

3. ICH Harmonized Tripartite Guideline E14 The clinical evaluation of QT/QT c interval prolongation and proarrhythmic potential for non-antiarrhythmic drugs 2012

4. Population pharmacokinetic and concentration-QTc models for moxifloxacin: pooled analysis of 20 thorough QT studies;Florian;J Clin Pharmacol,2011

5. Lamotrigine does not prolong QTc in a thorough QT/QTc study in healthy subjects;Dixon;Br J Clin Pharmacol,2008

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