HLA‐B*57:01 confers genetic susceptibility to carbamazepine‐induced SJS/TEN in Europeans

Author:

Mockenhaupt Maja1,Wang Chuang‐Wei234,Hung Shuen‐Iu45,Sekula Peggy6,Schmidt Alexander H.7,Pan Ren‐You23,Chen Chun‐Bing238910,Dunant Ariane11,Gouvello Sabine Le12,Schumacher Martin6,Valeyrie‐Allanore Laurence13,Bellon Teresa14,Kardaun Sylvia H.15,Jan Yun‐Shen23,Chung Wen‐Hung234810ORCID,Roujeau Jean‐Claude16,

Affiliation:

1. Dokumentationszentrum schwerer Hautreaktionen, Department of Dermatology, Faculty of Medicine and Medical Center University of Freiburg Freiburg Germany

2. Department of Dermatology, Drug Hypersensitivity Clinical and Research Center Chang Gung Memorial Hospital Linkou, Taipei and Keelung Taiwan

3. Chang Gung Immunology Consortium, Chang Gung Memorial Hospital and Chang Gung University Taoyuan Taiwan

4. Cancer Vaccine and Immune Cell Therapy Core Laboratory Chang Gung Memorial Hospital Linkou Taiwan

5. Department and Institute of Pharmacology, School of Medicine, Infection and Immunity Research Center National Yang‐Ming University Taipei Taiwan

6. Institute for Medical Biometry and Statistics, Faculty of Medicine and Medical Center University of Freiburg Freiburg Germany

7. DKMS German Bone Marrow Donor Center Tuebingen Germany

8. College of Medicine Chang Gung University Taoyuan Taiwan

9. Graduate Institute of Clinical Medical Sciences Chang Gung University Taoyuan Taiwan

10. Immune‐Oncology Center of Excellence Chang Gung Memorial Hospital Linkou Taiwan

11. Biostatistics and Epidemiology Unit Gustave Roussy Villejuif France

12. ImmunoBiology Department and Inserm U955 University Medical Center Henri Mondor Créteil France

13. Department of Dermatology AP‐HP, Hôpitaux Universitaires Henri Mondor Créteil France

14. Research Unit, Hospital La Paz Health Research Institute (IdiPAZ) Madrid Spain

15. Department of Dermatology, Reference Center for Cutaneous Adverse Reactions University Medical Center Groningen, University of Groningen Groningen The Netherlands

16. Université Paris‐Est Créteil Créteil France

Funder

European Commission

Deutsche Forschungsgemeinschaft

Ministry of Science and Technology, Taiwan

Publisher

Wiley

Subject

Immunology,Immunology and Allergy

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