Tumor necrosis factor alpha derived from classically activated “M1” macrophages reduces interstitial cell of Cajal numbers

Author:

Eisenman S. T.1,Gibbons S. J.1,Verhulst P. -J.1,Cipriani G.1,Saur D.2,Farrugia G.1

Affiliation:

1. Enteric NeuroScience Program; Mayo Clinic; Rochester MN USA

2. Department of Internal Medicine II; Klinikum rechts der Isar; Technische Universität München; München Germany

Funder

National Institutes of Health

Publisher

Wiley

Subject

Gastroenterology,Endocrine and Autonomic Systems,Physiology

Reference69 articles.

1. Mutation of the proto-oncogene c-kit blocks development of interstitial cells and electrical rhythmicity in murine intestine;Ward;J Physiol,1994

2. W/kit gene required for interstitial cells of Cajal and for intestinal pacemaker activity;Huizinga;Nature,1995

3. Interstitial cells of Cajal in health and disease;Farrugia;Neurogastroenterol Motil,2008

4. The muscle coat of the lower esophageal sphincter in patients with achalasia and hypertensive sphincter. An electron microscopic study;Faussone-Pellegrini;J Submicrosc Cytol,1985

5. Decreased interstitial cell of cajal volume in patients with slow-transit constipation;He;Gastroenterology,2000

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