Inhibition of Apoptosis Protects Mice from Ethanol-Mediated Acceleration of Early Markers of CCl4-Induced Fibrosis but not Steatosis or Inflammation-Reference-Cited by-同舟云学术

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Inhibition of Apoptosis Protects Mice from Ethanol-Mediated Acceleration of Early Markers of CCl4-Induced Fibrosis but not Steatosis or Inflammation

Published:2012-01-24 Issue:7 Volume:36 Page:1139-1147
ISSN:0145-6008
Container-title:Alcoholism: Clinical and Experimental Research
language:en
Short-container-title:Alcohol Clin Exp Res

Author:

Roychowdhury Sanjoy¹,Chiang Dian J.²,Mandal Palash¹,McMullen Megan R.¹,Liu Xiuli³,Cohen Jessica I.,Pollard John⁴,Feldstein Ariel E.,Nagy Laura E.

Affiliation:

1. Center for Liver Disease Research; Departments of Pathobiology; Case Western Reserve University; Cleveland; Ohio

2. Department of Gastroenterology; Case Western Reserve University; Cleveland; Ohio

3. Department of Anatomic Pathology; Cleveland Clinic; Case Western Reserve University; Cleveland; Ohio

4. Vertex Pharmaceuticals (Europe); Abingdon; UK

Publisher

Wiley

Subject

Psychiatry and Mental health,Toxicology,Medicine (miscellaneous)

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1111/j.1530-0277.2011.01720.x/fullpdf

Reference36 articles.

1. Impact of pan-caspase inhibition in animal models of established steatosis and non-alcoholic steatohepatitis;Anstee;J Hepatol,2010

2. Clinical trial of the pan-caspase inhibitor, IDN-6556, in human liver preservation injury;Baskin-Bey;Am J Transplant,2007

3. Subcellular changes and apoptosis induced by ethanol in rat liver;Benedetti;J Hepatol,1988

4. The caspase inhibitor IDN-6556 attenuates hepatic injury and fibrosis in the bile duct ligated mouse;Canbay;J Pharmacol Exp Ther,2004

5. Complement and alcoholic liver disease: role of C1q in the pathogenesis of ethanol-induced liver injury in mice;Cohen;Gastroenterology,2010

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