Insomnia, poor sleep quality and perinatal suicidal risk: A systematic review and meta‐analysis

Author:

Palagini Laura1,Cipriani Enrico2ORCID,Miniati Mario1,Bramante Alessandra2,Gemignani Angelo3,Geoffroy Pierre A.4567,Riemann Dieter8ORCID

Affiliation:

1. Department of Experimental and Clinical Medicine, Section of Psychiatry University of Pisa Pisa Italy

2. President of the Italian Section of the Marcè Society for Perinatal Psychopathology Milan Italy

3. Department of Surgical, Medical, Molecular, and Critical Area Pathology University of Pisa Pisa Italy

4. Department of Psychiatry and Addiction AP‐HP, GHU Paris Nord, DMU Neurosciences, Hôpital Bichat – Claude Bernard Paris France

5. Centre ChronoS, GHU Paris – Psychiatry & Neurosciences Paris France

6. Université Paris Cité, NeuroDiderot, Inserm Paris France

7. CNRS UPR 3212, Institute for Cellular and Integrative Neurosciences Strasbourg France

8. Department of Psychiatry and Psychotherapy, Medical Center‐ University of Freiburg, Faculty of Medicine University of Freiburg Freiburg Germany

Abstract

SummarySuicidal risk in mothers is a public health priority. Risk factors include biological, psychological and psychosocial factors. Among the biological factors, the role of sleep disturbances as potential contributors to increased suicidal risk during the peripartum period is becoming apparent. To explore this further, we conducted a systematic review following the PRISMA criteria. Currently, 10 studies have examined the role of insomnia and poor sleep quality in suicidal risk during the peripartum period and have involved 807,760 women. The data showed that disturbed sleep and poor sleep quality increase the risk of suicidal ideation in both pregnant women with and without perinatal depression. The results of the meta‐analysis indicated that insomnia and poor sleep quality increase the odds of suicidal risk in pregnant women by more than threefold (OR = 3.47; 95% CI: 2.63–4.57). Specifically, the odds ratio (OR) for poor sleep quality was 3.72 (95% CI: 2.58–5.34; p < 0.001), and for insomnia symptoms, after taking into account perinatal depression, was 4.76 (95% CI: 1.83–12.34; p < 0.001). These findings emphasise the importance of assessing and addressing sleep disturbances during the peripartum period to mitigate their adverse effects on peripartum psychopathology and suicidal risk.

Publisher

Wiley

Subject

Behavioral Neuroscience,Cognitive Neuroscience,General Medicine

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