Changes in arginine are inversely associated with type 2 diabetes: A case-cohort study in the PREDIMED trial

Author:

Yu Edward12,Ruiz-Canela Miguel345,Razquin Cristina3,Guasch-Ferré Marta156ORCID,Toledo Estefania345,Wang Dong D.1,Papandreou Christopher6ORCID,Dennis Courtney7,Clish Clary7,Liang Liming8,Bullo Monica6,Corella Dolores59,Fitó Montserrat59,Gutiérrez-Bedmar Mario10,Lapetra José511,Estruch Ramón512,Ros Emilio513,Cofán Montserrat513,Arós Fernando514,Romaguera Dora515,Serra-Majem Lluis516,Sorlí Jose V.59,Salas-Salvadó Jordi56,Hu Frank B.1217,Martínez-González Miguel A.134

Affiliation:

1. Department of Nutrition; Harvard T.H. Chan School of Public Health; Boston Massachusetts

2. Department of Epidemiology; Harvard T.H. Chan School of Public Health; Boston Massachusetts

3. Department of Preventive Medicine and Public Health; University of Navarra; Pamplona Spain

4. Medicina Preventiva y Salud Pública, IdiSNA (Instituto de Investigación Sanitaria de Navarra); Pamplona Spain

5. CIBER Fisiopatología de la Obesidad y Nutrición (CIBEROBN); Instituto de Salud Carlos III (ISCIII); Madrid Spain

6. Human Nutrition Unit; Faculty of Medicine and Health Sciences, Institut d'Investigació Sanitària Pere Virgili, Rovira i Virgili University; Reus Spain

7. Broad Institute of MIT and Harvard University; Cambridge Massachusetts

8. Department of Biostatistics; Harvard T.H. Chan School of Public Health; Boston Massachusetts

9. Department of Preventive Medicine; University of Valencia; Valencia Spain

10. Department of Preventive Medicine; University of Málaga; Málaga Spain

11. Department of Family Medicine, Unit Research; Distrito Sanitario Atención Primaria Sevilla; Sevilla Spain

12. Department of Internal Medicine, Institut d'Investigacions Biomèdiques August Pi Sunyer (IDI- BAPS); Hospital Clinic, University of Barcelona; Barcelona Spain

13. Lipid Clinic, Department of Endocrinology and Nutrition, IDIBAPS; Hospital Clinic, University of Barcelona; Barcelona Spain

14. Department of Cardiology; University Hospital of Álava; Vitoria Spain

15. Epidemiología Clínica y Salud Pública, Health Research Institute of Palma (IdISPa), University Hospital Son Espases; Palma de Mallorca Spain

16. Department of Clinical Sciences, Research Institute of Biomedical and Health Sciences, University of Las Palmas de Gran Canaria; Las Palmas Spain

17. Channing Division for Network Medicine, Department of Medicine; Brigham and Women's Hospital and Harvard Medical School; Massachusetts

Funder

National Institutes of Health

Instituto de Salud Carlos III

Ministerio de Economía y Competitividad

Generalitat Valenciana

American Diabetes Association

Publisher

Wiley

Subject

Endocrinology,Endocrinology, Diabetes and Metabolism,Internal Medicine

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