Affiliation:
1. Department of Diagnostic and Interventional Radiology Sir Charles Gairdner Hospital Perth Western Australia Australia
2. Breast Centre, Department of Diagnostic and Interventional Radiology Sir Charles Gairdner Hospital Perth Western Australia Australia
3. Breast Screen WA Perth Western Australia Australia
4. Department of Medical Imaging Fiona Stanley Hospital Perth Western Australia Australia
5. Perth Radiological Clinic Perth Western Australia Australia
6. University of Western Australia Perth Western Australia Australia
Abstract
AbstractIntroductionThe two most common types of breast cancer are invasive or infiltrating ductal carcinoma (IDC) and invasive or infiltrating lobular carcinoma (ILC) (Pestalozzi et al., J. Clin. Oncol., 26, 2008, 3006). Between 5% and 15% of invasive breast carcinomas are lobular carcinomas (Pestalozzi et al., J. Clin. Oncol., 26, 2008, 3006; Dossus and Benusiglio, Breast Cancer Res., 17, 2015, 37; Braunstein et al., Breast Cancer Res. Treat., 149, 2015, 555). The paucity of data relating to recurrence rates of lobular cancers prompted this study.MethodsA retrospective cohort study of all cases of lobular breast carcinoma reported to the Western Australia Cancer Registry with the clinical and pathological details between 2000 and 2014.ResultsOverall, 2463 subjects with a total of 2526 events of invasive lobular carcinoma of the breast. 11/2463 (0.45%) subjects met criteria for local recurrence of invasive lobular breast cancer, with an incidence of 1 in 224.ConclusionThere are clinical implications for the management and follow‐up for patients with a diagnosis of lobular cancer of the breast. Due to the low recurrence rate, now, the standard practice in our institution does not offer magnetic resonance imaging (MRI) as part of the follow‐up for ILC patients. Other centres should establish local recurrence rates to aid development of appropriate management protocols.