Interventional oncology in children: Where are we now?

Author:

Patel Premal Amrishkumar12ORCID,Muñoz Fernando Gómez34ORCID

Affiliation:

1. Interventional Radiology, Radiology Department Great Ormond Street Hospital for Children London UK

2. Developmental Biology and Cancer Research & Teaching Department UCL Great Ormond Street Institute of Child Health London UK

3. Interventional Radiology, Hospital Universitario y Politécnico La Fe Valencia Spain

4. Interventional Radiology Netherlands Cancer Institute Amsterdam The Netherlands

Abstract

AbstractPaediatric Interventional Oncology (IO) lags behind adult IO due to a scarcity of specific outcome data. The suboptimal way to evolve this field is relying heavily on adult experiences. The distinct tumour types prevalent in children, such as extracranial germ cell tumours, sarcomas, and neuroblastoma, differ strongly from those found in adults, presenting a completely different biological behaviour. Compounding this challenge, paediatric interventional radiology often employs adapted or off‐label techniques, potentially compromising optimal outcomes. This review outlines the present indications for interventional radiology in paediatric cancer, from biopsy to supportive care, including complication management. It emphasises the role of locoregional approaches, and explores the status of common paediatric oncological diseases, highlighting areas where IO has made progress identifying potential opportunities for future advancements in this evolving field.

Publisher

Wiley

Reference71 articles.

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