Proteomic profiling of TGFBI ‐null mouse corneas reveals only minor changes in matrix composition supportive of TGFBI knockdown as therapy against TGFBI ‐linked corneal dystrophies-Reference-Cited by-同舟云学术

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Proteomic profiling of TGFBI ‐null mouse corneas reveals only minor changes in matrix composition supportive of TGFBI knockdown as therapy against TGFBI ‐linked corneal dystrophies

Published:2017-11-23 Issue:1 Volume:285 Page:101-114
ISSN:1742-464X
Container-title:The FEBS Journal
language:en
Short-container-title:FEBS J

Author:

Poulsen Ebbe Toftgaard¹,Runager Kasper¹,Nielsen Nadia Sukusu¹²,Lukassen Marie V.¹²,Thomsen Karen²,Snider Paige³,Simmons Olga³,Vorum Henrik⁴⁵,Conway Simon J.³,Enghild Jan J.¹²

Affiliation:

1. Department of Molecular Biology and Genetics Aarhus University Denmark

2. Interdisciplinary Nanoscience Center Aarhus University Denmark

3. Herman B Wells Center for Pediatric Research Indiana University School of Medicine Indianapolis IN USA

4. Department of Ophthalmology Aalborg University Hospital Denmark

5. Department of Clinical Medicine Aalborg University Denmark

Funder

Sundhed og Sygdom, Det Frie Forskningsråd

Lundbeckfonden

Velux Fonden

National Institutes of Health

Fight for Sight

Publisher

Wiley

Subject

Cell Biology,Molecular Biology,Biochemistry

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1111/febs.14321

Reference58 articles.

1. Global estimates of visual impairment: 2010;Pascolini D;British J Ophthalmol,2012

2. Corneal dystrophies

3. Development of allele‐specific gene‐silencing siRNAs for TGFBI Arg124Cys in lattice corneal dystrophy type I;Courtney DG;Invest Ophthalmol Vis Sci,2014

4. TGFB1‐induced extracellular expression of TGFBIp and inhibition of TGFBIp expression by RNA interference in a human corneal epithelial cell line;Yellore VS;Invest Ophthalmol Vis Sci,2011

5. Suppression of keratoepithelin and myocilin by small interfering RNAs (siRNA) in vitro;Yuan C;Mol Vis,2007

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