Affiliation:
1. Liggins Institute University of Auckland Auckland New Zealand
2. Kidz First Neonatal Care Counties Manukau Health Auckland New Zealand
3. Department of Psychological Medicine University of Auckland Auckland New Zealand
4. Faculty of Education and Social Work University of Auckland Auckland New Zealand
Abstract
AbstractAimTo examine the relationship between neonatal hypoglycaemia and specific areas of executive function and behaviour in mid‐childhood.MethodParticipants in a prospective cohort study of infants born late preterm or at term at risk of neonatal hypoglycaemia were assessed at 9 to 10 years. We assessed executive function using performance‐based (Cambridge Neuropsychological Tests Automated Battery) and questionnaire‐based (Behavior Rating Inventory of Executive Function) measures and behaviour problems with the Strengths and Difficulties Questionnaire. Data are reported as adjusted odds ratio (aOR) with 95% confidence intervals, and standardized regression coefficients.ResultsWe assessed 480 (230 females, 250 males; mean age 9 years 5 months [SD 4 months, range 8 years 8 months–11 years 0 months]) of 587 eligible children (82%). There were no differences in performance‐based executive function between children who did and did not experience neonatal hypoglycaemia (blood glucose <2.6 mmoL/L). However, children who experienced hypoglycaemia, especially if severe or recurrent, were at greater risk of parent‐reported metacognition difficulties (aOR 2.37–3.71), parent‐reported peer (aOR 1.62–1.89) and teacher‐reported conduct (aOR 2.14 for severe hypoglycaemia) problems. Both performance‐ and questionnaire‐based executive functions were associated with behaviour problems.InterpretationNeonatal hypoglycaemia may be associated with difficulties in specific aspects of parent‐reported executive functions and behaviour problems in mid‐childhood.
Funder
Eunice Kennedy Shriver National Institute of Child Health and Human Development
Health Research Council of New Zealand
Maurice and Phyllis Paykel Trust
Subject
Neurology (clinical),Developmental Neuroscience,Pediatrics, Perinatology and Child Health
Cited by
1 articles.
订阅此论文施引文献
订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献