Diffuse Large B‐Cell Lymphoma in a Cynomolgus Monkey-Reference-Cited by-同舟云学术

Diffuse Large B‐Cell Lymphoma in a Cynomolgus Monkey

Published:2024-09-08 Issue:5 Volume:53 Page:
ISSN:0047-2565
Container-title:Journal of Medical Primatology
language:en
Short-container-title:J of Medical Primatology

Author:

Li Heling¹²^ORCID,Zhang Long³,Chen Zhigang¹²,Zong Faliang²,Tian Baohong¹,Chen Xinglong¹,Liu Deli²,Ning Qing¹,Wang Hong¹²^ORCID

Affiliation:

1. State Key Laboratory of Primate Biomedical Research, Institute of Primate Translational Medicine Kunming University of Science and Technology Kunming China

2. Yunnan Key Laboratory of Primate Biomedical Research Kunming China

3. Kunming Biomed International Ltd. Kunming China

Abstract

ABSTRACTA captive 17‐year‐old male cynomolgus monkey (Macaca fascicularis) developed diffuse large B‐cell lymphoma (DLBCL). This was the first report of DLBCL presenting with a mandible mass and violation of the paranasal sinus in a cynomolgus monkey. The neoplasm showed marked microscopical malignant aspects. Immunohistochemical staining showed strong positive expression of CD20. These features may contribute to the diagnosis and therapeutics of DLBCL in NHPs.

Publisher

Wiley

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1111/jmp.12734

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