Adnexal iceberg: pruritic papule on top of a nodule on the back

Author:

Dowdle Travis S.1,Holder Katherine G.1ORCID,Hope Landon1,Maldonado Dylan2ORCID,Billings Steven3,Tarbox Michelle2

Affiliation:

1. School of Medicine Texas Tech University Health Sciences Center Lubbock TX USA

2. Department of Dermatology Texas Tech University Health Sciences Center Lubbock TX USA

3. Cleveland Clinic Department of Dermatopathology Cleveland OH USA

Abstract

Abstract Basal cell carcinoma (BCC), one of the most common malignancies, is rarely associated with follicular and apocrine differentiation patterns. This case presents a case of BCC with atypical gross presentation and features of aberrant differentiation. Clinicians should maintain a high level of clinical suspicion for BCC in atypical lesions. Click here for the corresponding questions to this CME article.

Publisher

Oxford University Press (OUP)

Subject

Dermatology

Reference7 articles.

1. The many faces of basal-cell carcinoma;Wade;J Dermatol Surg Oncol,1978

2. Practical immunohistochemistry of epithelial skin tumor;Alhumaidi;Indian J Dermatol Venereol Leprol,2012

3. The use of BEREP4 Immunohistochemistry staining for detection of basal cell carcinoma;Sunjaya;J Skin Cancer,2017

4. Immunohistochemical nuclear staining for p53, PCNA, Ki-67 and bcl-2 in different histologic variants of basal cell carcinoma;Mateoiu;Rom J Morphol Embryol,2011

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