Using dinoprostone slow release vaginal insert for cervical ripening in term‐pregnancy with oligohydramnios

Abstract

AbstractAimsThe study purposed to evaluate the success rate of cervical ripening using dinoprostone controlled‐release vaginal insert and reveal some factors relating to successful cervical ripening.MethodsThis cross‐sectional study was conducted at Tu Du Hospital in Vietnam from December 2021 to August 2022. The study enrolled 200 pregnant women with gestational age ≥37 weeks diagnosed with oligohydramnios. These candidates underwent dinoprostone cervical ripening (DCR) according to the local protocol. The Bishop score ≥7 after 24 h was determined for the successful cervical ripening (SCR).ResultsIn total, the success rate of DCR achieved at 57.5% and the cesarean delivery rate was 46.5%. None of the severe side‐effects and complications was present. Using multivariable logistic regression, the study found that the body mass index ≥25 kg/m2 and oxytocin infusion drip related to SCR with adjusted odds ratio (aOR): 3.67 (95% confidence intervals [CI]: 1.78–7.57) and aOR: 4.68 (95% CI: 1.84–11.93), p < 0.001. Using the Kaplan–Meier curve, the present study revealed a significant difference between Bishop <3 and ≥3 following the duration time of cervical ripening, with hazard ratio: 1.38 (95% CI: 1.19–1.59), p < 0.001. The time duration of cervical ripening was not significantly different following amniotic fluid index from 3 to 5 cm.ConclusionsCervical ripening using a dinoprostone vaginal insert is a potentially acceptable method in term pregnancy accompanying with oligohydramnios. The probability of SCR can be predicted on a careful assessment of relative factors by obstetricians. Further studies are required to strengthen these findings.