Design, Synthesis and Biological Evaluation of Peptidyl Epoxyketone Proteasome Inhibitors Composed ofβ-amino Acids-Reference-Cited by-同舟云学术

Design, Synthesis and Biological Evaluation of Peptidyl Epoxyketone Proteasome Inhibitors Composed ofβ-amino Acids

Published:2014-06-03 Issue:5 Volume:84 Page:497-504
ISSN:1747-0277
Container-title:Chemical Biology & Drug Design
language:en
Short-container-title:Chem Biol Drug Des

Author:

Zhang Jiankang¹,Han Mengmeng²,Ma Xiaodong¹,Xu Lei²,Cao Jiayi²,Zhou Yubo²,Li Jia²,Liu Tao¹,Hu Yongzhou¹

Affiliation:

1. ZJU-ENS Joint Laboratory of Medicinal Chemistry; College of Pharmaceutical Sciences; Zhejiang University; Hangzhou 310058 China

2. National Center for Drug Screening; State Key Laboratory of Drug Research; Shanghai Institute of Materia Medica; Chinese Academy of Sciences; Shanghai 201203 China

Funder

National Natural Science Foundation of China

National Science and Technology Major Projects for Major New Drugs Innovation and Development

Publisher

Wiley

Subject

Molecular Medicine,Biochemistry,Drug Discovery,Pharmacology,Organic Chemistry

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1111/cbdd.12342/fullpdf

Reference20 articles.

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2. Proteasome inhibitors: recent advances and new perspectives in medicinal chemistry;Genin;Curr Top Med Chem,2010

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4. Structure of 20S proteasome from yeast at 2.4 A resolution;Groll;Nature,1997

5. The proteasome, a novel protease regulated by multiple mechanisms;DeMartino;J Biol Chem,1999

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