Further Insights Into the Pharmacology of the Human Trace Amine-Associated Receptors: Discovery of Novel Ligands for TAAR1 by a Virtual Screening Approach

Author:

Cichero Elena1,Espinoza Stefano2,Franchini Silvia3,Guariento Sara1,Brasili Livio3,Gainetdinov Raul R.245,Fossa Paola1

Affiliation:

1. Dipartimento di Farmacia; Università degli Studi di Genova; Viale Benedetto XV n. 3 Genova 16132 Italy

2. Department of Neuroscience and Brain Technologies; Istituto Italiano di Tecnologia; Via Morego 30, Genova 16163 Italy

3. Dipartimento di Scienze della Vita; Università degli Studi di Modena e Reggio Emilia; Via Campi 183 Modena 41100 Italy

4. Skolkovo Institute of Science and Technology; Skolkovo Moscow Region 143025 Russia

5. Faculty of Biology and Soil Science; St. Petersburg State University; St. Petersburg 199034 Russia

Publisher

Wiley

Subject

Molecular Medicine,Biochemistry,Drug Discovery,Pharmacology,Organic Chemistry

Reference26 articles.

1. A renaissance in trace amines inspired by a novel GPCR family;Lindemann;Trends Pharmacol Sci,2005

2. Trace amine-associated receptors as emerging therapeutic targets;Sotnikova;Mol Pharmacol,2009

3. Trace amines: identification of a family of mammalian G protein-coupled receptors;Borowsky;Proc Natl Acad Sci USA,2001

4. Trace amine-associated receptor 1 as a monoaminergic modulator in brain;Xie;Biochem Pharmacol,2009

5. Normal thermoregulatory responses to 3-iodothyronamine, trace amines and amphetamine-like psychostimulants in trace amine associated receptor 1 knockout mice;Panas;J Neurosci Res,2010

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