No remarkable differences in rates of sensitization to common type I and IV allergens betweenFLGloss-of-function mutation carriers and wild-type subjects
Author:
Affiliation:
1. Department of Dermatology, Environmental Medicine and Health Theory; University of Osnabrück; 49090 Osnabrück Germany
2. Coronel Institute of Occupational Health, Academic Medical Centre; University of Amsterdam; 1100 DE Amsterdam The Netherlands
Publisher
Wiley
Subject
Dermatology,Immunology and Allergy
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1111/cod.12109/fullpdf
Reference35 articles.
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2. Impact of loss-of-function mutations in the filaggrin gene and atopic dermatitis on the development of occupational irritant contact dermatitis;Visser;Br J Dermatol,2013
3. Clinical course of occupational irritant contact dermatitis of the hands in relation to filaggrin genotype status and atopy;Landeck;Br J Dermatol,2012
4. Filaggrin deficiency confers a paracellular barrier abnormality that reduces inflammatory thresholds to irritants and haptens;Scharschmidt;J Allergy Clin Immunol,2009
5. A homozygous frameshift mutation in the mouse Flg gene facilitates enhanced percutaneous allergen priming;Fallon;Nat Genet,2009
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