Whole blood transcriptional variations between responders and non‐responders in asthma patients receiving omalizumab

Author:

Upchurch Katherine1ORCID,Wiest Matthew12,Cardenas Jacob3,Skinner Jason3,Nattami Durgha3,Lanier Bobby4,Millard Mark5,Joo HyeMee12,Turner Jacob6,Oh SangKon12ORCID

Affiliation:

1. Baylor UniversityInstitute for Biomedical Studies Waco TX USA

2. Department of ImmunologyMayo Clinic Scottsdale AZ USA

3. Baylor Institute for Immunology Research Dallas TX USA

4. North Texas Institute for Clinical Trials Ft Worth TX USA

5. Martha Foster Lung Care CenterBaylor University Medical Center Dallas TX USA

6. Department of Mathematics and StatisticsStephen F. Austin State University Nacogdoches TX USA

Funder

American Asthma Foundation

Genentech

Publisher

Wiley

Subject

Immunology,Immunology and Allergy

Reference74 articles.

1. The anti‐inflammatory effects of omalizumab confirm the central role of IgE in allergic inflammation;Holgate S;J Allergy Clin Immunol,2005

2. Humanization of an antibody directed against IgE;Presta LG;J Immunol,1993

3. The binding site on human immunoglobulin E for its high affinity receptor;Presta L;J Biol Chem,1994

4. Anti‐IgE antibodies for the treatment of IgE‐mediated allergic diseases;Chang TW;Adv Immunol,2007

5. Fc epsilon receptor I on dendritic cells delivers IgE‐bound multivalent antigens into a cathepsin S‐dependent pathway of MHC class II presentation;Maurer D;J Immunol,1998

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