Bioavailability and safety of diazepam intranasal solution compared to oral and rectal diazepam in healthy volunteers-Reference-Cited by-同舟云学术

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Bioavailability and safety of diazepam intranasal solution compared to oral and rectal diazepam in healthy volunteers

Published:2020-03 Issue:3 Volume:61 Page:455-464
ISSN:0013-9580
Container-title:Epilepsia
language:en
Short-container-title:Epilepsia

Author:

Hogan R. Edward¹^ORCID,Gidal Barry E.²,Koplowitz Barry³,Koplowitz Luana P.³,Lowenthal Richard E.⁴,Carrazana Enrique⁵

Affiliation:

1. Department of Neurology Washington University in St Louis School of Medicine St Louis Missouri

2. School of Pharmacy University of Wisconsin Madison Wisconsin

3. DUCK FLATS Pharma Elbridge New York

4. Pacific Link Consulting San Diego California

5. Consultant for Neurelis Miami Florida

Funder

Neurelis, Inc.

Publisher

Wiley

Subject

Clinical Neurology,Neurology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1111/epi.16449

Reference25 articles.

1. Benzodiazepine use in seizure emergencies: A systematic review

2. A pilot study assessing the bioavailability and pharmacokinetics of diazepam after intranasal and intravenous administration in healthy volunteers

3. A review of intranasal formulations for the treatment of seizure emergencies

4. High efficiency intranasal drug delivery using Intravail® alkylsaccharide absorption enhancers

5. DFN-02 (Sumatriptan 10 mg With a Permeation Enhancer) Nasal Spray vs Placebo in the Acute Treatment of Migraine: A Double-Blind, Placebo-Controlled Study

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1. A Phase 1, Randomized, Open-label, Three-period Crossover Study to Evaluate Pharmacokinetics, Dose Proportionality, and Safety After Single Intranasal Administration of Diazepam Nasal Spray (NRL-1) in Healthy Japanese Participants;Rinsho yakuri/Japanese Journal of Clinical Pharmacology and Therapeutics;2024-07-31

2. Development of neffy, an Epinephrine Nasal Spray, for Severe Allergic Reactions;Pharmaceutics;2024-06-14

3. Development of a novel dosing paradigm to model diazepam rescue therapy in preclinical seizure and epilepsy models;Epilepsia Open;2024-06-13

4. Diazepam nasal spray administration is effective to control seizure clusters irrespective of time of day;Frontiers in Neurology;2024-05-24

5. Advances and future perspectives of intranasal drug delivery: A scientometric review;Journal of Controlled Release;2024-03

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