1. Department of Cardiology, Cardiothoracic Directorate Freeman Hospital Newcastle upon Tyne NHS Foundation Trust Newcastle upon Tyne UK
2. Biosciences Institute Newcastle University Newcastle upon Tyne UK
3. Clinical and Translational Research Institute Newcastle University Newcastle upon Tyne UK
4. Population Health Sciences Institute Newcastle University Newcastle upon Tyne UK
5. Cardiothoracic Surgery, Freeman Hospital Newcastle upon Tyne NHS Foundation Trust Newcastle upon Tyne UK