Platelet inhibitory effects of the Phase 3 anticancer and normal tissue cytoprotective agent, RR x‐001
Author:
Affiliation:
1. EpicentRx Inc La Jolla California
2. CFLS Data Mountain View California
3. Department of Bioengineering University of California San Diego La Jolla California
Funder
EpicentRx, Inc.
Publisher
Wiley
Subject
Cell Biology,Molecular Medicine
Link
https://onlinelibrary.wiley.com/doi/pdf/10.1111/jcmm.13791
Reference24 articles.
1. Endothelial nitric oxide synthase in red blood cells: Key to a new erythrocrine function?
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3. Nitrite reduction to nitric oxide by deoxyhemoglobin vasodilates the human circulation
4. Platelet Surface Collagen Receptor Polymorphisms: Variable Receptor Expression and Thrombotic/Hemorrhagic Risk
5. Biochemical evidence of a chronic abnormality in platelet and vascular function in healthy individuals who smoke cigarettes.
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1. RRx-001: a chimeric triple action NLRP3 inhibitor, Nrf2 inducer, and nitric oxide superagonist;Frontiers in Oncology;2023-05-29
2. Intravascularly infused extracellular matrix as a biomaterial for targeting and treating inflamed tissues;Nature Biomedical Engineering;2022-12-29
3. Clinical Course of Two Patients with COVID-19 Respiratory Failure After Administration of the Anticancer Small Molecule, RRx-001;International Medical Case Reports Journal;2022-12
4. Early Fresh Frozen Plasma Transfusion: Is It Associated With Improved Outcomes of Patients With Sepsis?;Frontiers in Medicine;2021-11-16
5. Discovery of RRx-001, a Myc and CD47 Downregulating Small Molecule with Tumor Targeted Cytotoxicity and Healthy Tissue Cytoprotective Properties in Clinical Development;Journal of Medicinal Chemistry;2021-05-27
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