Antagonism of Sigma‐1 receptor blocks heavy alcohol drinking and associated hyperalgesia in male mice

Author:

Quadir Sema G.1,Tanino Sean M.1,Sami Yasmine N.1,Minnig Margaret A.1,Iyer Malliga R.2ORCID,Rice Kenner C.3ORCID,Cottone Pietro1ORCID,Sabino Valentina1ORCID

Affiliation:

1. Laboratory of Addictive Disorders Departments of Pharmacology and Psychiatry Boston University School of Medicine Boston MA USA

2. Section on Medicinal Chemistry National Institute on Alcohol Abuse and Alcoholism Bethesda MD USA

3. Drug Design and Synthesis National Institute on Drug Abuse and National Institute on Alcohol Abuse and Alcoholism Bethesda MD USA

Funder

National Institute on Alcohol Abuse and Alcoholism

Publisher

Wiley

Subject

Psychiatry and Mental health,Toxicology,Medicine (miscellaneous)

Reference87 articles.

1. (2018 NSDUH) 2018 National Survey on Drug Use and Health (NSDUH) in Series 2018 National Survey on Drug Use and Health (NSDUH) www.samhsa.gov pp Table 5.4A—Alcohol Use Disorder in Past Year among Persons Aged 12 or Older by Age Group and Demographic Characteristics: Numbers in Thousands 2017 and 2018.

2. Immunocytochemical localization of the sigma1 receptor in the adult rat central nervous system

3. Central Amygdala Circuits Mediate Hyperalgesia in Alcohol-Dependent Rats

4. The Sigma Receptor as a Ligand-Regulated Auxiliary Potassium Channel Subunit

5. The Sigma-1 Receptor Binds to the Nav1.5 Voltage-gated Na+ Channel with 4-Fold Symmetry

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