PTENallelic loss is an important mechanism in the late stage of development of oral leucoplakia into oral squamous cell carcinoma

Author:

Miyahara Ligia A N1,Pontes Flávia S C2,Burbano Rommel M R2,Conte Neto Nicolau2,Guimarães Douglas M2,Fonseca Felipe P3ORCID,Pontes Hélder A R12ORCID

Affiliation:

1. Oral Diagnosis Department, Semiology and Oral Pathology Areas; Piracicaba Dental School; University of Campinas (UNICAMP); São Paulo Brazil

2. João de Barros; Barreto University Hospital (HUJBB); Federal University of Pará (UFPA); Pará Brazil

3. Department of Oral Surgery and Pathology; School of Dentistry; Federal University of Minas Gerais (UFMG); Minas Gerais Brazil

Funder

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior

Publisher

Wiley

Subject

General Medicine,Histology,Pathology and Forensic Medicine

Reference44 articles.

1. Oral and oropharynx cancer in South America: incidence, mortality trends and gaps in public databases as presented to the Global Oral Cancer Forum;Curado;Trans. Res. Oral Oncol.,2016

2. Squamous cell carcinoma of the tongue and floor of the mouth: analysis of survival rate and independent prognostic factors in the Amazon region;Pontes;J. Craniofac. Surg.,2011

3. Oral epithelial dysplasia classification systems: predictive value, utility, weaknesses and scope for improvement;Warnakulasuriya;J. Oral Pathol. Med.,2008

4. Observer variability in the histologic assessment of oral premalignant lesions;Karabulut;J. Oral Pathol. Med.,1995

5. MCM3 could be a better marker than Ki-67 for evaluation of dysplastic oral lesions: an immunohistochemical study;Lameira;J. Oral Pathol. Med.,2014

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