Expression of specific HLA class II alleles is associated with an increased risk for active tuberculosis and a distinct gene expression profile

Author:

Chihab Leila Y.12,Kuan Rebecca1,Phillips Elizabeth J.34,Mallal Simon A.34,Rozot Virginie5,Davis Mark M.67,Scriba Thomas J.5,Sette Alessandro18,Peters Bjoern18,Lindestam Arlehamn Cecilia S.1ORCID,

Affiliation:

1. Center for Infectious Disease and Vaccine Research La Jolla Institute for Immunology La Jolla California USA

2. Department of Chemistry and Biochemistry University of California San Diego La Jolla California USA

3. Institute for Immunology and Infectious Diseases Murdoch University Perth Western Australia Australia

4. Vanderbilt University School of Medicine Nashville Tennessee USA

5. South African Tuberculosis Vaccine Initiative, Institute of Infectious Disease and Molecular Medicine, Division of Immunology, Department of Pathology University of Cape Town Cape Town South Africa

6. Institute for Immunity, Transplantation and Infection Stanford University School of Medicine Stanford California USA

7. Howard Hughes Medical Institute Stanford University School of Medicine Stanford California USA

8. Department of Medicine University of California San Diego La Jolla California USA

Funder

National Institutes of Health

Publisher

Wiley

Subject

Genetics,Immunology,Immunology and Allergy

Reference52 articles.

1. WHO. (2020).Global Tuberculosis Report 2020.

2. The spectrum of latent tuberculosis: rethinking the biology and intervention strategies

3. Tuberculosis

4. WHO.The end TB strategy. (2017).

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