COVID‐19 outcomes in haemopoietic stem cell transplant recipients in Western Australia: the value of vaccination and antiviral therapy

Author:

Malherbe Jacques A. J.12ORCID,Boan Peter34ORCID,Purtill Duncan14,Wright Matthew14,Cannell Paul14,Gangatharan Shane A.124ORCID,Sidiqi Hasib14,Cooney Julian14ORCID

Affiliation:

1. Department of Haematology Fiona Stanley Hospital Perth Western Australia Australia

2. School of Biomedical Sciences, University of Western Australia Perth Western Australia Australia

3. Department of Infectious Diseases Fiona Stanley Hospital Perth Western Australia Australia

4. PathWest Laboratory Medicine Western Australia Perth Western Australia Australia

Abstract

AbstractCoronavirus‐19 (COVID‐19) mortality rates among haemopoietic stem cell transplant (HSCT) patients are high, ranging between 20% and 40%. We prospectively evaluated the mortality outcomes of COVID‐19 in Western Australian HSCT patients. A total of 32/492 (6.5%) HSCT recipients contracted COVID‐19 during the study, of whom 30/32 (94%) developed mild or asymptomatic disease. Two allogeneic HSCT patients were hospitalised for severe COVID‐19; one patient died. Stringent healthcare, social isolation practices, aggressive vaccination programmes and rapid access to COVID‐19 antivirals may have promoted mild COVID‐19 illness in Western Australian HSCT patients, resulting in one of the lowest COVID‐19 mortality rates in HSCT recipients worldwide.

Publisher

Wiley

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