Melatonin synergizes the chemotherapeutic effect of 5-fluorouracil in colon cancer by suppressing PI3K/AKT and NF-κB/iNOS signaling pathways-Reference-Cited by-同舟云学术

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Melatonin synergizes the chemotherapeutic effect of 5-fluorouracil in colon cancer by suppressing PI3K/AKT and NF-κB/iNOS signaling pathways

Published:2016-12-24 Issue:2 Volume:62 Page:e12380
ISSN:0742-3098
Container-title:Journal of Pineal Research
language:en
Short-container-title:J. Pineal Res.

Author:

Gao Yue¹²,Xiao Xiangsheng¹,Zhang Changlin¹,Yu Wendan²,Guo Wei²,Zhang Zhifeng²,Li Zhenglin²,Feng Xu²,Hao Jiaojiao²,Zhang Kefang³,Xiao Bingyi¹,Chen Miao¹,Huang Wenlin¹⁴,Xiong Shunbin⁵,Wu Xiaojun¹,Deng Wuguo¹⁴

Affiliation:

1. State Key Laboratory of Oncology in South China; Collaborative Innovation Center of Cancer Medicine; Sun Yat-sen University Cancer Center; Guangzhou China

2. Institute of Cancer Stem Cell; Dalian Medical University; Dalian China

3. Global Life Care Federation; Global Life Care Institute; Hong Kong China

4. State Key Laboratory of Targeted Drug for Tumors of Guangdong Province; Guangzhou Double Bioproduct Inc.; Guangzhou China

5. Department of Genetics; University of Texas MD Anderson Cancer Center; Houston TX USA

Funder

National Natural Science Foundation of China

State “973 Program” of China

Publisher

Wiley

Subject

Endocrinology

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1111/jpi.12380/fullpdf

Reference52 articles.

1. Ginsenoside compound K sensitizes human colon cancer cells to TRAIL-induced apoptosis via autophagy-dependent and -independent DR5 upregulation;Chen;Cell Death Dis,2016

2. Current concepts in rectal cancer;Fleshamn;Clin Colon Rectal Surg,2015

3. 5-fluorouracil: mechanisms of action and clinical strategies;Longley;Nat Rev Cancer,2003

4. Targeting the DNA replication checkpoint by pharmacologic inhibition of Chk1 kinase: a strategy to sensitize APC mutant colon cancer cells to 5-fluorouracil chemotherapy;Martino-Echarri;Oncotarget,2014

5. Functional mechanism of the enhancement of 5-fluorouracil sensitivity by TUSC4 in colon cancer cells;Liu;Oncol Lett,2015

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