The Synthesis and Evaluation of C7-Substitutedα-Tetralone Derivatives as Inhibitors of Monoamine Oxidase-Reference-Cited by-同舟云学术

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The Synthesis and Evaluation of C7-Substitutedα-Tetralone Derivatives as Inhibitors of Monoamine Oxidase

Published:2015-01-31 Issue:4 Volume:86 Page:895-904
ISSN:1747-0277
Container-title:Chemical Biology & Drug Design
language:en
Short-container-title:Chem Biol Drug Des

Author:

Legoabe Lesetja J.¹,Petzer Anél¹,Petzer Jacobus P.¹²

Affiliation:

1. Centre of Excellence for Pharmaceutical Sciences; North-West University; Private Bag X6001 Potchefstroom 2520 South Africa

2. Pharmaceutical Chemistry; School of Pharmacy; North-West University; Private Bag X6001 Potchefstroom 2520 South Africa

Funder

Medical Research Council and National Research Foundation of South Africa

Publisher

Wiley

Subject

Molecular Medicine,Biochemistry,Drug Discovery,Pharmacology,Organic Chemistry

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1111/cbdd.12508/fullpdf

Reference32 articles.

1. The scientific and clinical basis for the treatment of Parkinson disease;Olanow;Neurology,2009

2. Treatment of Parkinson's with L-Dopa. The early discovery phase, and a comment on current problems;Carlsson;J Neural Transm,2002

3. Review: management of Parkinson's disease;Pedrosa;Neuropsychiatr Dis Treat,2013

4. Adding a dopamine agonist to preexisting levodopa therapy vs. levodopa therapy alone in advanced Parkinson's disease: a meta analysis;Talati;Int J Clin Pract,2009

5. Levodopa and the progression of Parkinson's disease;Fahn;N Engl J Med,2004

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3. Discovery of novel 2-hydroxyl-4-benzyloxybenzyl aniline derivatives as potential multifunctional agents for the treatment of Parkinson's disease;European Journal of Medicinal Chemistry;2023-03

4. 6-Benzyloxyphthalides as selective and reversible monoamine oxidase B inhibitors with antioxidant and anti-neuroinflammatory activities for Parkinson’s disease treatment;Bioorganic Chemistry;2022-03

5. Research progress in pharmacological activities and structure-activity relationships of tetralone scaffolds as pharmacophore and fluorescent skeleton;European Journal of Medicinal Chemistry;2022-01

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