Repair gene O6-methylguanine-DNA methyltransferase is controlled by SP1 and up-regulated by glucocorticoids, but not by temozolomide and radiation

Author:

Aasland Dorthe1,Reich Thomas R.1,Tomicic Maja T.1,Switzeny Olivier J.1,Kaina Bernd1,Christmann Markus1ORCID

Affiliation:

1. Department of Toxicology; University Medical Center Mainz; Mainz Germany

Funder

Deutsche Krebshilfe

Publisher

Wiley

Subject

Cellular and Molecular Neuroscience,Biochemistry

Reference55 articles.

1. Activation of human O6-methylguanine-DNA methyltransferase gene by glucocorticoid hormone;Biswas;Oncogene,1999

2. p53-Mediated down-regulation of the human DNA repair gene O6-methylguanine-DNA methyltransferase (MGMT) via interaction with Sp1 transcription factor;Bocangel;Anticancer Res.,2009

3. Regulation of expression of the DNA repair gene O6-methylguanine-DNA methyltransferase via protein kinase C-mediated signaling;Boldogh;Can. Res.,1998

4. Clinical features, mechanisms, and management of pseudoprogression in malignant gliomas;Brandsma;Lancet Oncol.,2008

5. Activation of stress-responsive promoters by ionizing radiation for deployment in targeted gene therapy;Chastel;DNA Repair,2004

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