Selective late sodium current inhibitor GS-458967 suppresses Torsades de Pointes by mostly affecting perpetuation but not initiation of the arrhythmia-Reference-Cited by-同舟云学术

Selective late sodium current inhibitor GS-458967 suppresses Torsades de Pointes by mostly affecting perpetuation but not initiation of the arrhythmia

Published:2018-05-06 Issue:12 Volume:175 Page:2470-2482
ISSN:0007-1188
Container-title:British Journal of Pharmacology
language:en
Short-container-title:British Journal of Pharmacology

Author:

Bossu Alexandre¹^ORCID,Houtman Marien J C¹,Meijborg Veronique M F²,Varkevisser Rosanne¹,Beekman Henriette D M¹,Dunnink Albert¹,de Bakker Jacques M T¹²,Mollova Nevena³,Rajamani Sridharan⁴,Belardinelli Luiz⁵,van der Heyden Marcel A G¹^ORCID,Vos Marc A¹

Affiliation:

1. Department of Medical Physiology, Division Heart & Lungs; University Medical Center Utrecht; Utrecht The Netherlands

2. Department of Experimental Cardiology; Amsterdam Medical Center; Amsterdam The Netherlands

3. Gilead Sciences, Inc.; Foster City CA USA

4. Amgen; San Francisco CA USA

5. InCarda Therapeutics; Newark CA USA

Funder

Gilead Sciences

Publisher

Wiley

Subject

Pharmacology

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1111/bph.14217/fullpdf

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